Webinar

Assessing Pharmacokinetics and Manufacturability in Early Biologics Drug Discovery Webinar

Sep. 20, 2023

Assessing Pharmacokinetics and Manufacturability in Early Biologics Drug Discovery Webinar

Webinar title:

Assessing Pharmacokinetics and Manufacturability in Early Biologics Drug Discovery Webinar

Abstract:

In the early stages of biologics drug discovery, it’s crucial to have assays that reliably correlate with human pharmacokinetics (PK) and manufacturability. In this webinar, we introduce our advanced high-throughput analytical suite, designed to assess critical developability parameters. This comprehensive approach incorporates both in silico tools and diverse in vitro assays, including AC-SINS, Baculovirus/DNA/insulin ELISA, FcRn binding, Serum stability and others. Our panel is formatted in a 96WP design and requires only ~100ug of sample per assay, making it particularly suitable for the early lead ID/lead op stages.

You will gain valuable insight into:

How an integrated suite of developability assays can help evaluate the suitability of biologics as potential drugs at an early stage
How these micro developability tests use minimal material (<1 mg of protein) to allow lead molecules to be examined at an earlier stage.
Case studies demonstrating how these developability tests reliably correlate with human PK and manufacturability.

Speakers:

Han Yang, Assistant Director, Protein Sciences

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